Eosinophil Peroxidase MBS438346 from MyBioSource.com

Product Specs
ItemEosinophil Peroxidase
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS438346
Quantity0.1 mg
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH)
Conjugate/TagUnconjugated
ReactivityHuman
TargetEosinophil Peroxidase
IsotypeIgG1 kappa
Molecular Weight70kDa (55kDa-Heavy Chain; 15kDa-Light Chain)
CloneAHE-1
HostMouse
ImmunogenPeripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO)
NCBI Full Gene Nameeosinophil peroxidase
NCBI Gene AliasesEPO, EPX-PEN, EPP
ClonalityMonoclonal